| Date | Opponent | Result | Record | Notes |
| 12/02/52 | Furman | W 77-69 | 1-0 (1-0) | |
| 12/04/52 | Washington & Lee | W 88-63 | 2-0 (2-0) | |
| 12/06/52 | Davidson | W 82-47 | 3-0 (3-0) | |
| 12/09/52 | at Wake Forest | L 50-51 | 3-1 (3-1) | |
| 12/11/52 | Rhode Island | W 105-66 | 4-1 | |
| 12/13/52 | Eastern Kentucky | W 88-75 | 5-1 | |
| 12/18/52 | at George Washington | W 75-68 | 6-1 (4-1) | |
| 12/20/52 | Texas Tech | W 80-55 | 7-1 | |
| 12/23/52 | at St. John's | L 56-67 | 7-2 | |
| 12/27/52 | Dartmouth | W 96-50 | 8-2 | |
| 12/29/52 | Princeton | W 87-63 | 9-2 | Dixie Classic |
| 12/30/52 | Holy Cross | W 76-74 | 10-2 | Dixie Classic |
| 12/31/52 | Brigham Young | W 75-59 | 11-2 | Dixie Classic |
| 01/03/53 | at Cincinnati | W 77-72 | 12-2 | |
| 01/06/53 | at Davidson | W 105-71 | 13-2 (5-1) | |
| 01/10/53 | at Duke | W 82-64 | 14-2 (6-1) | |
| 01/13/53 | vs. William & Mary | W 62-58 | 15-2 (7-1) | Norfolk |
| 01/17/53 | George Washington | W 76-69 | 16-2 (8-1) | |
| 01/24/53 | North Carolina | L 69-70 | 16-3 (8-2) | |
| 01/28/53 | at Villanova | L 81-89 | 16-4 | |
| 01/31/53 | Wake Forest | W 99-80 | 17-4 (9-2) | |
| 02/04/53 | vs. South Carolina | W 91-51 | 18-4 (10-2) | Charlotte |
| 02/07/53 | William & Mary | W 101-71 | 19-4 (11-2) | |
| 02/11/53 | Villanova | W 94-72 | 20-4 | |
| 02/14/53 | Duke | L 82-84 | 20-5 (11-3) | |
| 02/17/53 | at Washington & Lee | W 108-69 | 21-5 (12-3) | |
| 02/24/53 | at North Carolina | W 87-86 | 22-5 (13-3) | |
| 02/??/53 | Fordham | W 73-70 | 23-5 | |
| 02/28/53 | Cincinnati | W 100-64 | 24-5 | |
| 03/05/53 | vs. North Carolina | W 86-54 | 25-5 | Southern Conference Tournament Rd. 1 |
| 03/06/53 | vs. West Virginia | W 85-80 | 26-5 | Southern Conference Semifinals |
| 03/07/53 | vs. Wake Forest | L 70-71 | 26-6 | Southern Conference Championship |
