| Date | Opponent | Result | Record | Notes |
| ??/??/?? | McCrary Eagles | W 60-47 | 1-0 | |
| ??/??/?? | McCrary Eagles | W 46-37 | 2-0 | |
| ??/??/?? | Georgetown (KY) | L 36-44 | 2-1 | |
| ??/??/?? | Hanes Hosiery | L 45-54 | 2-2 | |
| ??/??/?? | Hanes Hosiery | W 45-36 | 3-2 | |
| ??/??/?? | Davidson | W 71-36 | 4-2 (1-0) | |
| 01/13/42 | Clemson | W 52-36 | 5-2 (2-0) | |
| 01/20/42 | at North Carolina | L 28-41 | 5-3 (2-1) | |
| ??/??/42 | at College of Charleston | W 59-38 | 6-3 | |
| ??/??/42 | at Citadel | W 59-38 | 7-3 (3-1) | |
| ??/??/42 | Davidson | W 60-43 | 8-3 (4-1) | |
| ??/??/42 | Duke | L 28-40 | 8-4 (4-2) | |
| ??/??/42 | Wake Forest | L 43-44 | 8-5 (4-3) | |
| ??/??/42 | Citadel | W 60-40 | 9-5 (5-3) | |
| 02/12/42 | North Carolina | W 32-30 | 10-5 (6-3) | |
| ??/??/42 | Duke | L 48-53 | 10-6 (6-4) | |
| ??/??/42 | Wake Forest | W 44-38 | 11-6 (7-4) | |
| ??/??/42 | Virginia Tech | W 54-43 | 12-6 (8-4) | |
| ??/??/42 | South Carolina | W 64-54 | 13-6 (9-4) | |
| 03/05/42 | vs. South Carolina | W 56-43 | 14-6 | Southern Conference Tournament Rd. 1 |
| 03/06/42 | vs. William & Mary | W 53-52 | 15-6 | Southern Conference Semifinals |
| 03/07/42 | vs. Duke | L 34-45 | 15-7 | Southern Conference Championship |
